Article

Global propagation of genetic perturbation effects through genome-wide stoichiometry conservation architecture

2025-05-29

Abstract excerpt

Understanding how specific genetic changes lead organisms to different phenotypes is the cornerstone of genetics. However, even a single gene perturbation can cause global changes in gene expression profiles. Consequently, predicting which genes will be affected by a particular genetic perturbation remains a challenge. Here, we analyze changes in genome-wide gene expression profiles caused by single-gene perturbat...

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Literature Corpus work: 9d465546-421e-54da-99d2-736ee0dee485
DOI: 10.1101/2025.05.26.656078

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