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Article

Preservation of genetic and regulatory robustness in ancient gene duplicates of Saccharomyces cerevisiae.

Genome research - 1 Nov 2014

Keane Orla M, Toft Christina, Carretero-Paulet Lorenzo, Jones Gary W, Fares Mario A

Abstract excerpt

Biological systems remain robust against certain genetic and environmental challenges. Robustness allows the exploration of ecological adaptations. It is unclear what factors contribute to increasing robustness. Gene duplication has been considered to increase genetic robustness through functional redundancy, accelerating the evolution of novel functions. However, recent findings have questioned the link between...

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Identifiers

PMID: 25149527
DOI: 10.1101/gr.176792.114
PMCID: PMC4216924

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