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Article

Clinical and Genetic Analysis of KATP Variants With Heart Failure Risk in Patients With Decreased Serum ApoA-I Levels.

The Journal of clinical endocrinology and metabolism - 13 Jul 2021

Liu Cheng, Lai Yanxian, Pei Jingxian, Huang Huiling, Zhan Junfang, Ying Songsong, Shen Yan

Abstract excerpt

CONTEXT: Lower serum concentration of apolipoprotein A-I (ApoA-I) is causally associated with heart failure (HF) risk. Adenosine triphosphate-sensitive potassium channels (KATP), as gating channels coupling vascular reactivity and metabolism with ischemic protection, become a new potential target of management for HF. The KATP gene sequence is highly polymorphic and has a high degree of genetic heterogeneity....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33982099
DOI: 10.1210/clinem/dgab336

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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