Article
ATP-sensitive potassium channels gene polymorphism rs1799858 affects the risk of macro-/micro-vascular arteriosclerotic event in patients with increased low-density lipoprotein cholesterol levels.
Lipids in health and disease - 23 Jun 2020
Liu Cheng, Guan Tianwang, Lai Yanxian, Zhu Jieming, Kuang Jian, Shen Yan
Abstract excerpt
BACKGROUND: Plasma concentration of low-density lipoprotein cholesterol (LDL-C) is causally related to the risk of arteriosclerotic events. Whether ATP-sensitive potassium channels (KATP) genetic variants predict increased LDL-C concentration (≥1.8 mmol/L) and risk of macro-/micro-vascular arteriosclerotic event remain elusive. METHODS: A total of 320 subjects with increased LDL-C concentration (≥1.8 mmol/L) and...
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