Article

<i>ANGPTL8</i> protein-truncating variant and the risk of coronary disease, type 2 diabetes and adverse effects

2020-06-12

Abstract excerpt

Protein-truncating variants (PTVs) affecting dyslipidemia risk may point to therapeutic targets for cardiometabolic disease. Our objective was to identify PTVs that associated with both lipid levels and cardiometabolic disease risk and assess their possible associations with risks of other diseases. To achieve this aim, we leveraged the enrichment of PTVs in the Finnish population and tested the association of low...

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Literature Corpus work: 4bf1b5a6-cc43-515a-a08c-b2028d109436
DOI: 10.1101/2020.06.09.20125278

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