Leucine-rich repeat kinase 2-related functions in GLIA: an update of the last years.

Abstract excerpt

Missense mutations in the leucine-rich repeat kinase-2 (LRRK2) gene represent the most common cause of autosomal dominant Parkinson's disease (PD). In the years LRRK2 has been associated with several organelles and related pathways in cell. However, despite the significant amount of research done in the past decade, the contribution of LRRK2 mutations to PD pathogenesis remains unknown. Growing evidence...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Astrocytes
• Share to Brain
• Share to Genetic Predisposition to Disease