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Article

The role of LRRK2 in the periphery: link with Parkinson's disease and inflammatory diseases.

Neurobiology of disease - 1 Oct 2022

Tsafaras George, Baekelandt Veerle

Abstract excerpt

Parkinson's disease (PD) is currently considered a multisystemic disorder rather than a pure brain disease, in line with the multiple hit hypothesis from Braak. However, despite increasing evidence that the pathology might originate in the periphery, multiple unknown aspects and contradictory data on the pathological processes taking place in the periphery jeopardize the interpretation and therapeutic targeting...

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Identifiers

PMID: 35781002
DOI: 10.1016/j.nbd.2022.105806

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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