Article
Association of prostate cancer polygenic risk score with number and laterality of tumor cores in active surveillance patients.
The Prostate - 1 Jul 2021
Xu Jianfeng, Isaacs William B, Mamawala Mufaddal, Shi Zhuqing, Landis Patricia, Petkewicz Jacqueline, Wei Jun, Wang Chi-Hsiung, Resurreccion W Kyle, Na Rong, Bhanji Yasin, Novakovic Kristian, Walsh Patrick C, Zheng S Lilly, Helfand Brian T, Pavlovich Christian P
Abstract excerpt
BACKGROUND: Prostate cancer (PCa) is characterized by its tendency to be multifocal. However, few studies have investigated the endogenous factors that explain the multifocal disease. The primary objective of the current study is to test whether inherited PCa risk is associated with multifocal tumors in PCa patients. METHODS: Subjects in this study were PCa patients of European ancestry undergoing active...
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