Article
Genome-wide linkage scan for prostate cancer aggressiveness loci using families from the University of Michigan Prostate Cancer Genetics Project.
The Prostate - 1 Feb 2006
Slager Susan L, Zarfas Katherine E, Brown W Mark, Lange Ethan M, McDonnell Shannon K, Wojno Kirk J, Cooney Kathleen A
Abstract excerpt
BACKGROUND: Prostate cancer (PC) is a complex disease that displays variable disease outcome, ranging from a relatively indolent disease to forms that result in death from the disease. One measure of disease severity is the Gleason score. Using the Gleason score as a measure of tumor aggressiveness, several independent genome scans have reported evidence of linkage. As of yet, however, no genes have been...
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