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Article

Age and sex specific effects of APOE genotypes on ischemic heart disease and its risk factors in the UK Biobank.

Scientific reports - 29 Apr 2021

Li Mengyu, Zhao Jie V, Kwok Man Ki, Schooling C Mary

Abstract excerpt

APOE genotypes are associated with ischemic heart disease (IHD), several other cardiovascular diseases and dementia. Previous studies have not comprehensively considered all genotypes, especially ε2ε2, nor associations by age and sex, although IHD incidence differs by sex. In the UK Biobank, including 391,992 white British participants, we compared effects of APOE genotypes on IHD and its risk factors. Compared...

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Identifiers

PMID: 33927215
DOI: 10.1038/s41598-021-88256-x
PMCID: PMC8085204

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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