Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

APOE and vascular disease: Sequencing and genotyping in general population cohorts.

Atherosclerosis - 1 Nov 2023

Rasmussen Katrine L, Luo Jiao, Nordestgaard Børge G, Tybjærg-Hansen Anne, Frikke-Schmidt Ruth

Abstract excerpt

BACKGROUND AND AIMS: The apolipoprotein E(APOE) ϵ2/ϵ3/ϵ4 polymorphism plays a central role in lipid metabolism, vascular disease and dementia. The impact of the full range of structural genetic variation in APOE for lipids, lipoproteins and apolipoproteins and for vascular disease in the general population is not known. METHODS: We systematically sequenced APOE in 10,296 individuals from the Copenhagen City Heart...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Apolipoproteins E

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cholesterol

Share to Diabetes, Cardiovascular Risks, and Lipoproteins

Share to Genotype

Share to Myocardial Ischemia

Share to Triglycerides

Share to Vascular Diseases

Source

Identifiers

PMID: 37586954
DOI: 10.1016/j.atherosclerosis.2023.117218

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

APOE and vascular disease: Sequencing and genotyping in general population cohorts.PMID 37586954Read ↗

Apolipoprotein E (APOE) genotype-associated disease risks: a phenome-wide, registry-based, case-control study utilising the UK Biobank.Semantic proximity Read ↗

Age and sex specific effects of APOE genotypes on ischemic heart disease and its risk factors in the UK Biobank.Semantic proximity Read ↗

Apolipoprotein E genotype, cardiovascular biomarkers and risk of stroke: systematic review and meta-analysis of 14,015 stroke cases and pooled analysis of primary biomarker data from up to 60,883 individuals.Semantic proximity Read ↗

Apolipoprotein E (APOE) Haplotypes in Healthy Subjects from Worldwide Macroareas: A Population Genetics Perspective for Cardiovascular Disease, Neurodegeneration, and DementiaSemantic proximity Read ↗

Impact of Apolipoprotein E Variants: A Review of Naturally Occurring Variants and Clinical FeaturesSemantic proximity Read ↗

The relation between apolipoprotein E (APOE) genotype and peripheral artery disease in patients at high risk for cardiovascular disease.Semantic proximity Read ↗

Genetically Predicted Apolipoprotein E Levels with the Risk of Panvascular Diseases: A Mendelian Randomization Study.Semantic proximity Read ↗

Additive Effect of APOE Rare Variants on the Phenotype of Familial Hypercholesterolemia.Semantic proximity Read ↗

Circulating Apolipoprotein E Concentration and Cardiovascular Disease Risk: Meta-analysis of Results from Three Studies.Semantic proximity Read ↗

ApoE plasma levels and risk of cardiovascular mortality in old age.Semantic proximity Read ↗

Rare and common variants in the Apolipoprotein E gene in healthy oldest old.Semantic proximity Read ↗

APOE and dementia - resequencing and genotyping in 105,597 individuals.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.