Article

APOB to estimated APOB ratio for screening for the APOE2 genotype

2026-01-30

Abstract excerpt

<h4>Background</h4> Familial dysbetalipoproteinemia (FDB) is a genetic lipoprotein disorder that can develop in patients homozygous for the APOE2 genotype (ε2/ε2). It is associated with decreased clearance of remnant lipoproteins and increased atherosclerotic cardiovascular disease (ASCVD) risk disproportionate to their level of LDL-C. A goal of this study was to develop a screening test for the ε2/ε2 genotype ba...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: c5dfeacb-e236-56c0-8a53-7bc9403a4f4e
DOI: 10.64898/2026.01.29.26345063

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

APOB to estimated APOB ratio for screening for the APOE2 genotypeDOI 10.64898/2026.01.29.26345063Read

Diagnosis of Familial Dysbetalipoproteinemia Based on the Lipid Abnormalities Driven by APOE2/E2 Genotype.Semantic proximity Read

Prevalence of Dysbetalipoproteinemia in the UK Biobank According to Different Diagnostic CriteriaSemantic proximity Read

Evaluation of biochemical algorithms to screen dysbetalipoproteinemia in ε2ε2 and rare APOE variants carriers.Semantic proximity Read

Roles of high apolipoprotein E blood levels and HDL in development of familial dysbetalipoproteinemia in ε2ε2 subjects.Semantic proximity Read

Apolipoprotein E-ε2 and Resistance to Atherosclerosis in Midlife: The PESA Observational Study.Semantic proximity Read

Apolipoprotein E (APOE) genotype-associated disease risks: a phenome-wide, registry-based, case-control study utilising the UK Biobank.Semantic proximity Read

Establishing the relationship between familial dysbetalipoproteinemia and genetic variants in the APOE gene.Semantic proximity Read

Genetic risk score in patients with the APOE2/E2 genotype as a predictor of familial dysbetalipoproteinemia.Semantic proximity Read

<i>ApoE</i> e2 and aging-related outcomes in 379,000 UK Biobank participantsSemantic proximity Read

A simplified diagnosis algorithm for dysbetalipoproteinemia.Semantic proximity Read

Phenome-Wide Association of<i>APOE</i>Alleles in the<i>All of Us</i>Research ProgramSemantic proximity Read

ApoE e2 and aging-related outcomes in 379,000 UK Biobank participants.Semantic proximity Read