Article
Inhibition of β-Catenin Activity Abolishes LKB1 Loss-Driven Pancreatic Cystadenoma in Mice.
International journal of molecular sciences - 28 Apr 2021
Hsieh Mei-Jen, Weng Ching-Chieh, Lin Yu-Chun, Wu Chia-Chen, Chen Li-Tzong, Cheng Kuang-Hung
Abstract excerpt
Pancreatic cancer (PC) is the seventh leading cause of cancer death worldwide, and remains one of our most recalcitrant and dismal diseases. In contrast to many other malignancies, there has not been a significant improvement in patient survival over the past decade. Despite advances in our understanding of the genetic alterations associated with this disease, an incomplete understanding of the underlying biology...
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