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Article

Catechol-O-methyltransferase genetic variant associated with the risk of Alzheimer's disease in a Brazilian population.

Dementia and geriatric cognitive disorders - 1 Jan 2012

Pereira Patricia Araújo, Romano-Silva Marco Aurélio, Bicalho Maria Aparecida Camargos, de Moraes Edgar Nunes, Malloy-Diniz Leandro, Pimenta Guilherme José Garcia Santos, Mello Marina Pena, Bozzi Isadora Cristine Reis Sguizzato, de Marco Luiz Armando, Nicolato Rodrigo, Miranda Debora Marques

Abstract excerpt

The aim of the present study was to examine the association between polymorphism in the catechol-O-methyltransferase(COMT) gene and Alzheimer's disease (AD) in a Brazilian population. The case-control method was used to study the association between AD and genetic variants of COMT. Six tag single-nucleotide polymorphisms(SNPs) in the COMT gene were genotyped by RT-PCR. Our findings showed that the 6 tag SNPs...

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Source

Identifiers

PMID: 22922787
DOI: 10.1159/000341578

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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