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Article

Correlations between COMT polymorphism and brain structure and cognition in elderly subjects: An observational study.

Medicine - 6 May 2022

Cha Eunsil, Ahn Hyun Jung, Kang Wonil, Jung Kwang-Ik, Ohn Suk Hoon, Bashir Shahid, Yoo Woo-Kyoung

Abstract excerpt

ABSTRACT: The catechol-O-methyltransferase (COMT) gene has been noted to play an important role in individual variations in the aging process. We investigated whether COMT polymorphism could influence cognition related to white matter networks. More specifically, we examined whether methionine (Met) allele loading is associated with better individual cognitive performance. Thirty-four healthy elderly participants...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 35550471
DOI: 10.1097/MD.0000000000029214
PMCID: PMC9276462

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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