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Article

LRRK2 at the Crossroad of Aging and Parkinson's Disease.

Genes - 29 Mar 2021

Hur Eun-Mi, Lee Byoung Dae

Abstract excerpt

Parkinson's disease (PD) is a heterogeneous neurodegenerative disease characterized by the progressive loss of dopaminergic neurons in the substantia nigra pars compacta and the widespread occurrence of proteinaceous inclusions known as Lewy bodies and Lewy neurites. The etiology of PD is still far from clear, but aging has been considered as the highest risk factor influencing the clinical presentations and the...

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Identifiers

PMID: 33805527
DOI: 10.3390/genes12040505
PMCID: PMC8066012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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