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Pathological and Therapeutic Advances in Parkinson’s Disease: Mitochondria in the Interplay

6 Sept 2022

Abstract excerpt

Parkinson's disease (PD) is the second most common neurodegenerative illness majorly affecting the population between the ages of 55 to 65 years. Progressive dopaminergic neuronal loss and the collective assemblage of misfolded alpha-synuclein in the substantia nigra, remain notable neuro-pathological hallmarks of the disease. Multitudes of mechanistic pathways have been proposed in attempts to unravel the...

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PMID: 36093711
DOI: 10.3233/jad-220682

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