Article
Molecular Pathways Involved in LRRK2-Linked Parkinson's Disease: A Systematic Review.
International journal of molecular sciences - 3 Oct 2022
Ravinther Ailyn Irvita, Dewadas Hemaniswarri Dewi, Tong Shi Ruo, Foo Chai Nien, Lin Yu-En, Chien Cheng-Ting, Lim Yang Mooi
Abstract excerpt
Parkinson's disease is one of the most common neurodegenerative diseases affecting the ageing population, with a prevalence that has doubled over the last 30 years. As the mechanism of the disease is not fully elucidated, the current treatments are unable to effectively prevent neurodegeneration. Studies have found that mutations in Leucine-rich-repeat-kinase 2 (LRRK2) are the most common cause of familial...
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