Article
Balancing Positive and Negative Selection: In Vivo Evolution of Candida lusitaniae MRR1.
mBio - 30 Mar 2021
Demers Elora G, Stajich Jason E, Ashare Alix, Occhipinti Patricia, Hogan Deborah A
Abstract excerpt
The evolution of pathogens in response to selective pressures present during chronic infections can influence their persistence and virulence and the outcomes of antimicrobial therapy. Because subpopulations within an infection can be spatially separated and the host environment can fluctuate, an appreciation of the pathways under selection may be most easily revealed through the analysis of numerous isolates...
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