Article
Participation of the ABC Transporter CDR1 in Azole Resistance of Candida lusitaniae
15 Sept 2021
Abstract excerpt
Candida lusitaniae is an opportunistic pathogen in humans that causes infrequent but difficult-to-treat diseases. Antifungal drugs are used in the clinic to treat C. lusitaniae infections, however, this fungus can rapidly acquire antifungal resistance to all known antifungal drugs (multidrug resistance). C. lusitaniae acquires azole resistance by gain-of-function (GOF) mutations in the transcriptional regulator...
Topics
Join the communities discussing this publication.
