Article

Balancing positive and negative selection: <i>in vivo</i> evolution of <i>Candida lusitaniae MRR1</i>

2020-12-01

Abstract excerpt

The evolution of pathogens in response to selective pressures present during chronic infections can influence persistence, virulence, and the outcomes of antimicrobial therapy. Because subpopulations within an infection can be spatially separated and the host environment can fluctuate, an appreciation of the pathways under selection may be most easily revealed through the analysis of numerous isolates from single...

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Literature Corpus work: 85825733-a753-5588-822c-19c86a84a928
DOI: 10.1101/2020.11.30.405712

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