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Article

Accelerated mutator phenotype in a clinical Aspergillus fumigatus isolate contributes to adaptive evolution.

Emerging microbes & infections - 1 Dec 2026

Song Yinggai, Hokken Margriet W J, Zoll Jan, Venselaar Hanka, Verweij Paul E, Melchers Willem J G, Rhodes Johanna

Abstract excerpt

The opportunistic pathogen Aspergillus fumigatus represents a major threat to immunocompromised individuals and is increasingly resistant to antifungal therapies. Resistance selection primarily takes place through environmental selection to azole fungicides, but in-host resistance may develop in patients with chronic aspergillosis receiving azole therapy. In this study, we examine clinical A. fumigatus isolates...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41838943
DOI: 10.1080/22221751.2026.2627078
PMCID: PMC12997362

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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