Article
A modified sleeping beauty transposon system that can be used to model a wide variety of human cancers in mice.
Cancer research - 15 Oct 2009
Dupuy Adam J, Rogers Laura M, Kim Jinsil, Nannapaneni Kishore, Starr Timothy K, Liu Pentao, Largaespada David A, Scheetz Todd E, Jenkins Nancy A, Copeland Neal G
Abstract excerpt
Recent advances in cancer therapeutics stress the need for a better understanding of the molecular mechanisms driving tumor formation. This can be accomplished by obtaining a more complete description of the genes that contribute to cancer. We previously described an approach using the Sleeping B...
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