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Article

Whole-Genome Transformation Promotes tRNA Anticodon Suppressor Mutations under Stress.

mBio - 23 Mar 2021

Deparis Quinten, Duitama Jorge, Foulquié-Moreno Maria R, Thevelein Johan M

Abstract excerpt

tRNAs are encoded by a large gene family, usually with several isogenic tRNAs interacting with the same codon. Mutations in the anticodon region of other tRNAs can overcome specific tRNA deficiencies. Phylogenetic analysis suggests that such mutations have occurred in evolution, but the driving force is unclear. We show that in yeast suppressor mutations in other tRNAs are able to overcome deficiency of the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33758086
DOI: 10.1128/mBio.03649-20
PMCID: PMC8092322

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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