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Article

tRNA genes rapidly change in evolution to meet novel translational demands.

eLife - 20 Dec 2013

Yona Avihu H, Bloom-Ackermann Zohar, Frumkin Idan, Hanson-Smith Victor, Charpak-Amikam Yoav, Feng Qinghua, Boeke Jef D, Dahan Orna, Pilpel Yitzhak

Abstract excerpt

Changes in expression patterns may occur when organisms are presented with new environmental challenges, for example following migration or genetic changes. To elucidate the mechanisms by which the translational machinery adapts to such changes, we perturbed the tRNA pool of Saccharomyces cerevisiae by tRNA gene deletion. We then evolved the deletion strain and observed that the genetic adaptation was recurrently...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24363105
DOI: 10.7554/eLife.01339
PMCID: PMC3868979

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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