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Notch Signaling Pathway in Cancer—Review with Bioinformatic Analysis

12 Feb 2021

Abstract excerpt

Notch signaling is an evolutionarily conserved pathway regulating normal embryonic development and homeostasis in a wide variety of tissues. It is also critically involved in carcinogenesis, as well as cancer progression. Activation of the Notch pathway members can be either oncogenic or suppressive, depending on tissue context. The present study is a comprehensive overview, extended with a bioinformatics...

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PMID: 33673145
DOI: 10.3390/cancers13040768

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