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Targeting Notch signaling pathways with natural bioactive compounds: a promising approach against cancer

18 Jul 2024

Abstract excerpt

Notch signaling pathway is activated abnormally in solid and hematological tumors, which perform essential functions in cell differentiation, survival, proliferation, and angiogenesis. The activation of Notch signaling and communication among Notch and other oncogenic pathways heighten malignancy aggressiveness. Thus, targeting Notch signaling offers opportunities for improved survival and reduced disease...

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PMID: 39092224
DOI: 10.3389/fphar.2024.1412669

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