Article
Notch Pathway: A Journey from Notching Phenotypes to Cancer Immunotherapy.
Advances in experimental medicine and biology - 1 Jan 2021
Monticone Giulia, Miele Lucio
Abstract excerpt
Notch is a key evolutionary conserved pathway, which has fascinated and engaged the work of investigators in an uncountable number of biological fields, from development of metazoans to immunotherapy for cancer. The study of Notch has greatly contributed to the understanding of cancer biology and a substantial effort has been spent in designing Notch-targeting therapies. Due to its broad involvement in cancer,...
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