Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Notch signaling pathway: a comprehensive prognostic and gene expression profile analysis in breast cancer

7 Dec 2022

Abstract excerpt

Breast cancer is a complex disease exhibiting a great degree of heterogeneity due to different molecular subtypes. Notch signaling regulates the differentiation of breast epithelial cells during normal development and plays a crucial role in breast cancer progression through the abnormal expression of the Notch up-and down-stream effectors. To date, there are only a few patient-centered clinical studies using...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Cancer-related molecular mechanisms research
Share to Epigenetics and DNA Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36476410
DOI: 10.1186/s12885-022-10383-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Notch signaling pathway: a comprehensive prognostic and gene expression profile analysis in breast cancerPMID 36476410Read ↗

A comprehensive analysis of notch signaling genes in breast cancer: Expression pattern and prognostic significanceSemantic proximity Read ↗

A comprehensive analysis of Notch signalling genes in breast cancer: Expression pattern and prognostic significanceSemantic proximity Read ↗

Notch Signaling Pathway as a Therapeutic Target in Breast CancerSemantic proximity Read ↗

Notch signaling pathway in cancer: from mechanistic insights to targeted therapiesSemantic proximity Read ↗

A novel subtype classification and risk of breast cancer by histone modification profiling.Semantic proximity Read ↗

Notch Signaling Pathway in Cancer—Review with Bioinformatic AnalysisSemantic proximity Read ↗

The clinical significance of the expression of PROM1/CD133, NOTCH2 and CDK4 in triple-negative breast cancerSemantic proximity Read ↗

DNA Methylation Based Molecular Subtypes Predict Prognosis in Breast Cancer PatientsSemantic proximity Read ↗

Epigenetic markers of tumor progression in estrogen receptor–positive breast cancer patients with high nodal involvementSemantic proximity Read ↗

A functional Notch–survivin gene signature in basal breast cancerSemantic proximity Read ↗

A “NOTCH” Deeper into the Epithelial-To-Mesenchymal Transition (EMT) Program in Breast CancerSemantic proximity Read ↗

NOTCH Pathway Genes in Ovarian Cancer: Clinical Significance and Associations with Immune Cell InfiltrationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.