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Article

The Effect of GBA Mutations and APOE Polymorphisms on Dementia with Lewy Bodies in Ashkenazi Jews.

Journal of Alzheimer's disease : JAD - 1 Jan 2021

Shiner Tamara, Mirelman Anat, Rosenblum Yevgenia, Kavé Gitit, Weisz Mali Gana, Bar-Shira Anat, Goldstein Orly, Thaler Avner, Gurevich Tanya, Orr-Urtreger Avi, Giladi Nir, Bregman Noa

Abstract excerpt

BACKGROUND: Glucocerebrosidase (GBA) gene mutations and APOE polymorphisms are common in dementia with Lewy bodies (DLB), however their clinical impact is only partially elucidated. OBJECTIVE: To explore the clinical impact of mutations in the GBA gene and APOE polymorphisms separately and in combination, in a cohort of Ashkenazi Jewish (AJ) patients with DLB. METHODS: One hundred consecutively recruited AJ...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33646158
DOI: 10.3233/JAD-201295
PMCID: PMC8150431

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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