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Drug and apoptosis resistance in cancer stem cells (CSCs): A puzzle with many pieces

1 Jan 2022

Abstract excerpt

Resistance to anticancer agents and apoptosis results in cancer relapse and is associated with cancer mortality. Substantial data have provided convincing evidence establishing that human cancers emerge from cancer stem cells (CSCs), which display self-renewal and are resistant to anticancer drugs, radiation, and apoptosis, and express enhanced epithelial to mesenchymal progression. CSCs represent a heterogeneous...

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PMID: 36627897
DOI: 10.20517/cdr.2022.20

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