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Article

The role of cancer stem cells in tumor heterogeneity and resistance to therapy

3 Sept 2016

Abstract excerpt

Cancer is a heterogenous disease displaying marked inter- and intra-tumoral diversity. The existence of cancer stem cells (CSCs) has been experimentally demonstrated in a number of cancer types as a subpopulation of tumor cells that drives the tumorigenic and metastatic properties of the entire cancer. Thus, eradication of the CSC population is critical for the complete ablation of a tumor. This is, however,...

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PMID: 27925473
DOI: 10.1139/cjpp-2016-0079

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