Article
At the crossroads of cancer stem cells and targeted therapy resistance.
Cancer letters - 28 Jan 2017
Wang Anbang, Qu Le, Wang Linhui
Abstract excerpt
Small-molecule targeted therapy (TT) has brought great hopes to patients with advanced malignancies. However, most patients suffer from tumor progression and relapse due to drug resistance. Recently, considerable efforts trying to elucidate the underlying mechanisms have focused on the contribution of cancer stem cells (CSCs) to the targeted therapy resistance (TTR). In this article, we provide an overview of the...
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