Article
Shedding Light on Mutant Clonal Dynamics and Cancer Risk in the Skin.
Cancer discovery - 1 Feb 2021
De Dominici Marco, DeGregori James
Abstract excerpt
In this issue of Cancer Discovery, Fowler and colleagues conduct a thorough characterization of the dynamics of mutant clones in phenotypically normal human skin. Their results extend previous studies by showing that human skin is composed in large part of clones harboring mutations frequently observed in human cancer, while at the same time they uncover a previously unappreciated biological heterogeneity among...
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