Article
Brain-derived neurotrophic factor Val66Met variant on brain volumes in infants.
Brain structure & function - 1 Apr 2021
Kawasaki Yukako, Oishi Kenichi, Hernandez Antonette, Ernst Thomas, Wu Dan, Otsuka Yoshihisa, Ceritoglu Can, Chang Linda
Abstract excerpt
The brain-derived neurotrophic factor (BDNF) has many important roles in neurogenesis and neuronal health. BDNF is also involved in learning and memory. Individuals with BDNF-Val66Met variant (Met +) are at higher risk for neuropsychiatric disorders and have smaller hippocampi and amgydalae compared to those without this variant (Met -). Whether these smaller brain volumes are already present at birth is unknown...
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