Article
Mutation Maker, An Open Source Oligo Design Platform for Protein Engineering.
ACS synthetic biology - 19 Feb 2021
Hiraga Kaori, Mejzlik Petr, Marcisin Matej, Vostrosablin Nikita, Gromek Anna, Arnold Jakub, Wiewiora Sebastian, Svarba Rastislav, Prihoda David, Clarova Kamila, Klempir Ondrej, Navratil Josef, Tupa Ondrej, Vazquez-Otero Alejandro, Walas Marcin W, Holy Lukas, Spale Martin, Kotowski Jakub, Dzamba David, Temesi Gergely, Russell Jay H, Marshall Nicholas M, Murphy Grant S, Bitton Danny A
Abstract excerpt
Protein engineering is the discipline of developing useful proteins for applications in research, therapeutic, and industrial processes by modification of naturally occurring proteins or by invention of de novo proteins. Modern protein engineering relies on the ability to rapidly generate and screen diverse libraries of mutant proteins. However, design of mutant libraries is typically hampered by scale and...
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