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Article

Insight into Vaccine Development for Alphacoronaviruses Based on Structural and Immunological Analyses of Spike Proteins

8 Jan 2021

Abstract excerpt

(HCoV-229E) with a RBD "lying" state, the S-trimer may be more suitable for subunit vaccines than the RBD. Our results will provide novel ideas for the development of vaccines targeting S protein in the future.

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Identifiers

PMID: 33414160
DOI: 10.1128/jvi.02284-20

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