Article
The structural characterization and antigenicity of the S protein of SARS-CoV.
Genomics, proteomics & bioinformatics - 1 May 2003
Li Jingxiang, Luo Chunqing, Deng Yajun, Han Yujun, Tang Lin, Wang Jing, Ji Jia, Ye Jia, Jiang Fanbo, Xu Zhao, Tong Wei, Wei Wei, Zhang Qingrun, Li Shengbin, Li Wei, Li Hongyan, Li Yudong, Dong Wei, Wang Jian, Bi Shengli, Yang Huanming
Abstract excerpt
The corona-like spikes or peplomers on the surface of the virion under electronic microscope are the most striking features of coronaviruses. The S (spike) protein is the largest structural protein, with 1,255 amino acids, in the viral genome. Its structure can be divided into three regions: a long N-terminal region in the exterior, a characteristic transmembrane (TM) region, and a short C-terminus in the...
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