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Insight into vaccine development for Alpha-coronaviruses based on structural and immunological analyses of spike proteins

2020-06-09

Abstract excerpt

Coronaviruses that infect humans belong to the Alpha-coronavirus (including HCoV-229E) and Beta-coronavirus (including SARS-CoV and SARS-CoV-2) genera. In particular, SARS-CoV-2 is currently a major threat to public health worldwide. However, no commercial vaccines against the coronaviruses that can infect humans are available. The spike (S) homotrimers bind to their receptors through the receptor-binding domain...

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Identifiers and source

Literature Corpus work
b2912d6e-999a-5838-a0ed-ad8e20c4b861
DOI
10.1101/2020.06.09.141580
Open publication

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Insight into vaccine development for Alpha-coronaviruses based on structural and immunological analyses of spike proteinsDOI 10.1101/2020.06.09.141580
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