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Article

The INO80 Complex Regulates Epigenetic Inheritance of Heterochromatin.

Cell reports - 29 Dec 2020

Shan Chun-Min, Bao Kehan, Diedrich Jolene, Chen Xiao, Lu Chao, Yates John R, Jia Songtao

Abstract excerpt

One key aspect of epigenetic inheritance is that chromatin structures can be stably inherited through generations after the removal of the signals that establish such structures. In fission yeast, the RNA interference (RNAi) pathway is critical for the targeting of histone methyltransferase Clr4 to pericentric repeats to establish heterochromatin. However, pericentric heterochromatin cannot be properly inherited...

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Share to Chromatin Assembly and Disassembly
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33378674
DOI: 10.1016/j.celrep.2020.108561
PMCID: PMC7896557

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