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Article

Epigenetics. Restricted epigenetic inheritance of H3K9 methylation.

Science (New York, N.Y.) - 3 Apr 2015

Audergon Pauline N C B, Catania Sandra, Kagansky Alexander, Tong Pin, Shukla Manu, Pidoux Alison L, Allshire Robin C

Abstract excerpt

Posttranslational histone modifications are believed to allow the epigenetic transmission of distinct chromatin states, independently of associated DNA sequences. Histone H3 lysine 9 (H3K9) methylation is essential for heterochromatin formation; however, a demonstration of its epigenetic heritability is lacking. Fission yeast has a single H3K9 methyltransferase, Clr4, that directs all H3K9 methylation and...

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Share to Heterochromatin
Share to Histone-Lysine N-Methyltransferase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lysine

Share to Methylation

Share to Methyltransferases

Share to Protein Processing, Post-Translational

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Share to Schizosaccharomyces pombe Proteins

Source

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Identifiers

PMID: 25838386
DOI: 10.1126/science.1260638
PMCID: PMC4397586

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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