Predicting the Future of Genetic Risk Profiling of Glaucoma: A Narrative Review.

Abstract excerpt

Importance: Glaucoma is the world's leading cause of irreversible blindness. Primary open-angle glaucoma (POAG) is typically asymptomatic early in the disease process, and unfortunately, many are diagnosed too late to prevent vision loss. Observations: Genome-wide association studies, which evaluate the association between genetic variants and phenotype across the genome, have mapped many genes for POAG. As well...

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