Article
The Smc5/6 Core Complex Is a Structure-Specific DNA Binding and Compacting Machine.
Molecular cell - 17 Dec 2020
Serrano Diego, Cordero Gustavo, Kawamura Ryo, Sverzhinsky Aleksandr, Sarker Muzaddid, Roy Shamayita, Malo Catherine, Pascal John M, Marko John F, D'Amours Damien
Abstract excerpt
The structural organization of chromosomes is a crucial feature that defines the functional state of genes and genomes. The extent of structural changes experienced by genomes of eukaryotic cells can be dramatic and spans several orders of magnitude. At the core of these changes lies a unique group of ATPases-the SMC proteins-that act as major effectors of chromosome behavior in cells. The Smc5/6 proteins play...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.