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Article

Positive and negative regulation of SMC-DNA interactions by ATP and accessory proteins.

The EMBO journal - 7 Jul 2004

Hirano Michiko, Hirano Tatsuya

Abstract excerpt

Structural maintenance of chromosomes (SMC) proteins are central regulators of higher-order chromosome dynamics from bacteria to humans. The Bacillus subtilis SMC (BsSMC) homodimer adopts a V-shaped structure with an ATP-binding catalytic domain at each end. We report here that two small proteins, ScpA and ScpB, associate with the catalytic domains of BsSMC in an ordered fashion and suppress its ATPase activity....

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Share to Adenosine Triphosphatases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Centrifugation, Density Gradient

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Identifiers

PMID: 15175656
DOI: 10.1038/sj.emboj.7600264
PMCID: PMC449774

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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