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Article

Conserved disruptions in the predicted coiled-coil domains of eukaryotic SMC complexes: implications for structure and function.

Genome research - 1 Aug 2002

Beasley Matthew, Xu Huiling, Warren William, McKay Michael

Abstract excerpt

The structural maintenance of chromosome (SMC) proteins are required for a number of essential nuclear processes, including those of chromosome condensation, chromatid cohesion, and DNA repair. Eukaryotic SMC proteins form heterodimers capable of binding DNA and possess a DNA-stimulated ATPase activity. They have a characteristic structure of terminal globular domains with two internal arms that are predicted to...

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Identifiers

PMID: 12176928
DOI: 10.1101/gr107302
PMCID: PMC186632

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Conserved disruptions in the predicted coiled-coil domains of eukaryotic SMC complexes: implications for structure and function.PMID 12176928Read ↗

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An asymmetric SMC-kleisin bridge in prokaryotic condensin.Semantic proximity Read ↗

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