Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of the single deaminase domain APOBEC3A in virus restriction, retrotransposition, DNA damage and cancer

21 Oct 2015

Abstract excerpt

The apolipoprotein mRNA editing enzyme catalytic polypeptide-like 3 (APOBEC3; A3) proteins are a family of seven cytidine deaminases (A3A, A3B, A3C, A3D, A3F, A3G and A3H) that restrict certain viral infections. These innate defence factors are best known for their ability to restrict the replication of human immunodeficiency virus type 1 (HIV-1) lacking a functional Vif protein (HIV-1Δvif) through the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytomegalovirus and herpesvirus research
Share to HIV Research and Treatment
Share to RNA regulation and disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26489798
DOI: 10.1099/jgv.0.000320

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of the single deaminase domain APOBEC3A in virus restriction, retrotransposition, DNA damage and cancerPMID 26489798Read ↗

APOBEC3 family proteins as drivers of virus evolutionSemantic proximity Read ↗

Antiviral Mechanism and Biochemical Basis of the Human APOBEC3 FamilySemantic proximity Read ↗

Cytidine Deaminases as a Weapon Against Retroviruses and a New Target for Antiviral TherapySemantic proximity Read ↗

The APOBEC3 Cytidine Deaminases: An Innate Defensive Network Opposing Exogenous Retroviruses and Endogenous RetroelementsSemantic proximity Read ↗

Evolutionarily conserved and non-conserved retrovirus restriction activities of artiodactyl APOBEC3F proteins.Semantic proximity Read ↗

Multiple APOBEC3 Restriction Factors for HIV-1 and One Vif to Rule Them AllSemantic proximity Read ↗

The role of cytidine deaminases on innate immune responses against human viral infections.Semantic proximity Read ↗

Human APOBEC3 Variations and Viral InfectionSemantic proximity Read ↗

Loop 1 of APOBEC3C regulates its antiviral activity against HIV-1Semantic proximity Read ↗

Structural perspectives on HIV‐1 Vif and APOBEC3 restriction factor interactionsSemantic proximity Read ↗

The double-domain cytidine deaminase APOBEC3G is a cellular site-specific RNA editing enzymeSemantic proximity Read ↗

APOBEC3C tandem domain proteins create super restriction factors against HIV-1Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.