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Article

APOBEC-mediated editing of viral RNA.

Science (New York, N.Y.) - 30 Jul 2004

Bishop Kate N, Holmes Rebecca K, Sheehy Ann M, Malim Michael H

Abstract excerpt

Retroviral DNA can be subjected to cytosine-to-uracil editing through the action of members of the APOBEC family of cytidine deaminases. Here we demonstrate that APOBEC-mediated cytidine deamination of human immunodeficiency virus (HIV) virion RNA can also occur. We speculate that the natural sub...

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Identifiers

PMID: 15286366
DOI: 10.1126/science.1100658

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15286366-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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