Article
APOBEC3 Interference during Replication of Viral Genomes.
Viruses - 11 Jun 2015
Willems Luc, Gillet Nicolas Albert
Abstract excerpt
Co-evolution of viruses and their hosts has reached a fragile and dynamic equilibrium that allows viral persistence, replication and transmission. In response, infected hosts have developed strategies of defense that counteract the deleterious effects of viral infections. In particular, single-strand DNA editing by Apolipoprotein B Editing Catalytic subunits proteins 3 (APOBEC3s) is a well-conserved mechanism of...
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