Article
Refinement of coding SNPs in the human aryl hydrocarbon receptor gene using ISNPranker: An integrative-SNP ranking web-tool.
Computational biology and chemistry - 1 Feb 2021
Aftabi Younes, Rafei Saleh, Zarredar Habib, Amiri-Sadeghan Amir, Akbari-Shahpar Mohsen, Khoshkam Zahra, Seyedrezazadeh Ensiyeh, Khalili Majid, Mehrnejad Faramarz, Fereidouni Sasan, Lawrence B Paige
Abstract excerpt
Different bioinformatic methods apply various approaches to predict how much the effect of a SNP could be deleterious and therefore their results may differ significantly. However, variation studies often need to consider an integrated prediction result to analyze the effect of SNPs. To address this problem, we used an algorithm to map ordinal predictions to a numeral space and averaging them, and based on it we...
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