Article
Computational study of ADD1 gene polymorphism associated with hypertension.
Cell biochemistry and biophysics - 1 Jan 2013
Kundu Arpita, Anand Anbarasu
Abstract excerpt
We have determined the non-synonymous single-nucleotide polymorphisms (nsSNPs) of α adducin 1 (ADD1) gene and its variations in different populations to understand its role in hypertension. Out of 1,113 SNPs, 9 are found to be non-synonymous, of which 7 showed significant damaging effect and one of them showed SNP variability with large differences among the minor allele frequency observed in various populations....
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